Richards, J.E. (submitted). Cortical sources of ERP in the prosaccade and antisaccade task using realistic source models based on individual MRIs. Psychophysiology. (PDF)
The cortical sources of event-related-potentials (ERP) using realistic source models were examined in a prosaccade and antisaccade task. College-age participants were presented with a preparatory interval and a target that indicated the direction of the eye movement that was to be made. In some blocks a cue was given in the peripheral location where the target was to be presented and in other blocks no cue was given. An Independent Components Analysis (ICA) of the EEG resulted in component clusters representing a central negative slow wave prior to the target, a positive wave and spike potential immediately prior to the saccade, and a positive potential about 70 ms prior to saccade over frontal pole electrode locations. The negative pretarget slow wave and the positive presaccadic slow wave were based on a common set of brain areas located in the anterior cingulate cortex and cingulate gyrus, but did not discriminate prosaccade and antisaccade eye movements. The frontal pole activity was related to the cueing and the type of eye movement, and its cortical sources were located in several areas of the prefrontal cortex.